DIASAFE^® plus

Dialysis fluid filter

It is designed for the ultrapure fluid production for the dialysis needs.

The quality and the purity of the dialysis fluid are of major concern in renal replacement therapies, as large volumes of dialysis fluid come into contact with the patient’s bloodstream during each treatment.

In treatments, such as hemodiafiltration, in which large fluid volumes are exchanged, the quality and purity of the substitution fluid are of even greater importance.

Bacterial endotoxins and other microbial contaminations present in dialysis fluid may elicit undesirable acute reactions and influence long-term patient outcomes. In order to avoid endotoxin-related complications in dialysis, the usage of ultra pure dialysis fluid is strongly recommended.

Dialysis systems not containing the bacteria and endotoxins retention filter:
"The samples have to be taken in the systems on the regular basis  in order to ensure the effectiveness of the disinfection process verification. The sample collection schedule depends on the type of the disinfection process used. The samples have to be taken in each system at least once a year and in some systems the samples have to be taken every time. Most frequently the monthly monitoring is accepted. "(ref. ISO 23500: 2011 chapter 8.3)
"Tests for bacteria growing and endotoxins are not required if the system is equipped with the bacteria and endotoxins retention filter approved by the manufacturer, and which is operated and monitored in accordance with the manufacturer's instructions, unless the manufacturer  doesn’t require these tests in the operating instructions." (ref. ISO 23500: 2011 chapter 7.2.3)

All dialysis systems not containing the bacteria and endotoxins retention filter (e.g. DIASAFE plus) should be controlled at least once a year.

The routine production of ultra pure dialysis fluid and substitution fluid relies on the implementation of ultrafilters – such as DIASAFEplus

Ultra pure dialysis fluid – Dialysis fluid having a high degree of purity with endotoxins below 0.03 IU/mL.

The routine application of ultra pure dialysis fluid helps to reduce dialysis-related inflammation. Moreover, it improves the control of anaemia, making it an important cornerstone of cardioprotective hemodialysis.